---
title: "Research"
description: "SecureCattle® is a high quality, easy to use pour-on solution, that allows cattle to better control their reactions to stress."
url: "https://www.securecattleus.com/research"
date: "2026-06-05T11:29:25+00:00"
language: "en-GB"
---

There has been a significant amount of research published in leading scientific journals globally that has established the benefit of maternal bovine appeasing substance (mBAS) use in cattle of all ages and stages to alleviate stress and improve productivity and well-being.

All mBAS research published prior to 2023 was done using SecureCattle by the IRSEA/SIGNS group.

### PERFORMANCE

![increased average daily gain](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons.png)

![body weight](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons2.png)

![feed efficiency](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons3.png)

![weaning weight](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons4.png)

![decreased transport shrink](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons5.png)

### HEALTH

![increased treatment success](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons10.png)

![immune response](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons11.png)

![early detection](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons12.png)

![decreased re-treatment](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons13.png)

![decreased morbidity](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons14.png)

### MATERNAL

![increased weaning process](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons6.png)

![decreased calving difficulty](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons7.png)

![retained placentia](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons8.png)

![metritis](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons9.png)

### LACTATION

![increased milk production](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons15.png)

![decreased somatic cell count](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons16.png)

![risk of ketosis](https://www.securecattleus.com/images/2025/04/09/securecattle_researchicons17.png)

### WHAT THE RESEARCH SAYS

[ Effects of a synthetic analogue of the bovine appeasing pheromone on the overall welfare of dairy calves from birth through weaning
J. Garcia-Alvarez, E. Teruel, A. Cozzi, E. Harris, S. M. Rutter, and A. Beaver, *Journal of Dairy Science*, Volume 108, Issue 2, 1964 - 1977 ](https://www.securecattleus.com/media/attachments/2025/03/25/alvarez-et-a-2024-birth-through-weaning.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/alvarez-et-a-2024-birth-through-weaning.pdf)

[ Effects of an Appeasing Substance Application at Weaning on Growth, Stress, Behavior, and Response to Vaccination of *Bos indicus* Calves
Vieira, D.G., Vedovatto, M., Fernandes, H.J., Lima, E.d.A., D’Oliveira, M.C., Curcio, U.d.A., Ranches, J., Ferreira, M.F., Sousa, O.A.d., Cappellozza, B.I., et a, *Animals*, Volume 13, No. 19: 3033](https://www.securecattleus.com/media/attachments/2025/03/25/vieira-et-al-2023-response-to-vaccination.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/vieira-et-al-2023-response-to-vaccination.pdf)

[ Strategic administration of an appeasing substance to improve performance and physiological responses of *Bos indicus* feedlot cattle
Victor G L Fonseca, Bruno I Cappellozza, Osvaldo A de Sousa, Manuella Sagawa, Bruna Rett, Mário L Chizzotti, Reinaldo F Cooke, *Journal of Animal Science*, Volume 99, Issue 11, November 2021, skab322](https://www.securecattleus.com/media/attachments/2025/03/25/fonseca-et-al-2021-feedlot-cattle.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/fonseca-et-al-2021-feedlot-cattle.pdf)

[ Appeasing Pheromones against Bovine Respiratory Complex and Modulation of Immune Transcript Expressions
Hervet C, Boullier J, Guiadeur M, Michel L, Brun-Lafleur L, Aupiais A, Zhu J, Mounaix B, Meurens F, Renois F, Assié S., *Animals* (Basel). 2021 May 25;11(6):1545.](https://www.securecattleus.com/media/attachments/2025/03/25/hervet-et-al-2021-immune-transcript-expressions.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/hervet-et-al-2021-immune-transcript-expressions.pdf)

[ Administering an appeasing substance to beef calves at weaning to optimize productive and health responses during a 42-d preconditioning program
Schubach KM, Cooke RF, Daigle CL, Brandão AP, Rett B, Ferreira VSM, Scatolin GN, Colombo EA, D'Souza GM, Pohler KG, Cappellozza BI., *Journal of Animal Science*, 2020 Sep 1; 98(9).](https://www.securecattleus.com/media/attachments/2025/03/25/schubach-et-al-2020-42day-preconditioning.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/schubach-et-al-2020-42day-preconditioning.pdf)

[ Administering an Appeasing Substance to Gir × Holstein Female Dairy Calves on Pre-Weaning Performance and Disease Incidence
Angeli B, Cappellozza B, Moraes Vasconcelos JL, Cooke RF., *Animals* (Basel). 2020 Oct 24;10(11):1961](https://www.securecattleus.com/media/attachments/2025/03/25/angeli-et-al-2020-gir-x-holstein.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/angeli-et-al-2020-gir-x-holstein.pdf)

[ Short communication: administering an appeasing substance to Bos indicus-influenced beef cattle at weaning and feedlot entry
R.F. Cooke, A. Millican, A.P. Brandão, T.F. Schumaher, O.A. de Sousa, T. Castro, R.S. Farias, B.I. Cappellozza, *Animal*, Volume 14, Issue 3, 2020](https://www.securecattleus.com/media/attachments/2025/03/25/cooke-et-al-2019-weaning-and-feedlot-entry.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/cooke-et-al-2019-weaning-and-feedlot-entry.pdf)

[ Short communication: Administration of an appeasing substance to *Bos indicus*-influenced beef cattle improves performance after weaning and carcass pH
Cappellozza, Bruno & Bastos, J.P. & Cooke, Reinaldo, *Livestock Science*, 238. 104067. 10.1016, 2020](https://www.securecattleus.com/media/attachments/2025/03/25/cappellozza-et-al-2020-after-weaning-and-carcass-ph.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/cappellozza-et-al-2020-after-weaning-and-carcass-ph.pdf)

[ Administering an appeasing substance to optimize performance and health responses in feedlot receiving cattle
Colombo EA, Cooke RF, Brandão AP, Wiegand JB, Schubach KM, Duff GC, Gouvêa VN, Cappellozza BI., *Journal of Animal Science*, 2020 Nov 1;98(11).](https://pubmed.ncbi.nlm.nih.gov/33068399/)

[View Study](https://pubmed.ncbi.nlm.nih.gov/33068399/)

[ The effects of a synthetic analogue of the Bovine Appeasing Pheromone on milk yield and composition in Valdostana dairy cows during the move from winter housing to confined lowland pastures
Osella MC, Cozzi A, Spegis C, Turille G, Barmaz A, Lecuelle CL, Teruel E, Bienboire-Frosini C, Chabaud C, Bougrat L, Pageat P., *The Journal of Dairy Research* 2018 May;85(2)](https://www.securecattleus.com/media/attachments/2025/03/25/osella-et-al-2018-milk-yield.pdf)

[View Study](https://www.securecattleus.com/media/attachments/2025/03/25/osella-et-al-2018-milk-yield.pdf)

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